Giant congenital melanocytic nevus GCMN is a rare disorder affecting 1 in 200,000–500,000 live births. It is regarded as giant when it involves more than 20 cm in greatest dimension or >9 cm in the scalp or more than 6 cm in the trunk. In about 82% cases, the disease is axially distributed.

A congenital pigmented or melanocytic nevus is a dark-colored, often hairy, patch of skin. A congenital nevus is present at birth or appears in the first year of life. A giant congenital nevus is smaller in infants and children, but it usually continues to grow as the child grows. A giant pigmented nevus is larger than 8 inches once it stops.

19.02.2019 · BACKGROUND: A giant congenital melanocytic nevus GCMN is found in 0.1% of live-born infants. If present, the lesion has a chance of about 6% to develop into malignant melanoma. Both children and adults can be affected by malignant melanoma arising in a giant congenital nevus. Up to 95% of GCMNs harbor NRAS mutations, and mutations in the BRAF.

Giant congenital melanocytic nevus - Causes and Consequences Some days ago we heard about Lucas, a patient from Alaska who has giant congenital melanocytic nevus. He is only 12 years old but this disease has conditioned his health and social life since he can remember.

23.01.2018 ·.A giant congenital melanocytic nevus is a birthmark that covers more than two per cent, or 20cm, of a sufferer's body and requires more than one incision to remove.The head, legs and arms are.

This infant was noted to have a giant melanocytic nevus at birth. Giant congenital melanocytic nevi GCMN can be recognized not only by their increased size greater than 20 cm but also by their increased cellularity and ability to affect deep dermal layers and other subcutaneous tissue.

Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous.

Tethered Cord Syndrome Parenchymal Involvement Congenital Melanocytic Nevus Leptomeningeal Involvement Meningeal Melanocytoma These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

A Congenital Melanocytic Nevus is a birthmark, it can be defined as small, large, and giant. They are not genetic, and there are several different types.

A small congenital melanocytic naevus is < 1.5 cm in diameter. A medium congenital melanocytic naevi is 1.5–19.9 cm. A large or giant congenital melanocytic naevus is ≥ 20 cm in diameter. A modification of the above criteria is used in some centres [2].